The FiFo director has already been honoured with the Ruhr Prize for Art and Science of the City of Mülheim an der Ruhr in 2021. Due to the pandemic, the festive award ceremony could only take place now. Following Michael Thöne's laudation in which he praised Klaus Mackscheidt as a scientist and a true Renaissance man, Lord Mayor Marc Buchholz presented him with the Ruhr Prize, the highest honour that Mülheim bestows. Klaus Mackscheidt also signed the Golden Book of his native city.